piRPheno is a manually curated database platform that provides experimentally supported associations between piRNAs and disease phenotypes. piRNAs have been experimentally validated as a novel class of biomarkers and potential drug targets for disease diagnosis, therapy and prognosis. The discovery of relationships between piRNAs and disease phenotypes has become increasingly important. piRPheno provides experimentally validated associations between piRNAs and disease phenotypes through manual curation on publications. piRPheno provides user-friendly web interfaces and RESTful application programming interfaces for users to browse, search, prioritize, analyze and access data freely. To cite piRPheno: Wenliang Zhang et al.. piRPheno: a manually curated database to prioritize and analyze human disease related piRNAs. bioRxiv 2020.10.09.334219; doi: https://doi.org/10.1101/2020.10.09.334219
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